The different techniques of Assisted Reproductive Technology (ART) or In Vitro Fertilization (IVF)


Embarking on the journey of fertility treatment can be a daunting task for couples facing the challenges of infertility. While the diagnoses and examinations may seem intimidating, they hold the key to personalized recommendations from fertility experts. To guide you through this process, we delve into four effective IVF techniques: IUI, IVF, ICSI, and IMSI, carefully selected to suit the specific needs of each individual couple.

IVF :Popular destination for IVF

Tunisia has rapidly gained popularity as a highly desirable destination for In Vitro Fertilization (IVF) on a global scale, drawing in individuals from all corners of the world. This North African country has seen a rise in visitors from Algeria, West Africa, Libya, Mauritania, and even Europe, seeking out IVF treatments within its borders. It’s noteworthy to mention that Tunisia is proudly home to the largest IVF center in Africa, firmly establishing itself as a prominent leader in the realm of assisted reproductive technology.As one sets out on the demanding path of fertility treatments, the tranquil vistas and welcoming hospitability of Tunisia beckon. Beyond the state-of-the-art medical centers that provide comfort and hope, patients also embrace the diverse community that promotes acceptance and empathy.

The choice to undergo IVF is an intensely personal one, and Tunisia’s emergence as a leading destination for this advanced medical procedure is a testament to its dedication to offering top-notch fertility services. Boasting a team of expert practitioners and cutting-edge technology, the nation shines as a guiding light for those in search of effective reproductive solutions.One of the main draws of Tunisia is its geographical beauty, but what truly sets it apart as a top choice for those seeking fertility treatments is its easy accessibility from Europe and its excellent healthcare system. Furthermore, the diversity found within the country guarantees that patients will feel comfortable and accepted, making the entire IVF journey even more enriching.

IVF Technology

IUI: IntraUterine Insemination with spouse’s sperm

IntraUterine Insemination is the oldest IVF technique. The husband’s sperm is placed in the female genital tract (cervix or uterine cavity). With ovarian stimulation and sperm preparation before insemination, the goal is to facilitate the meeting of oocytes/spermatozoa while selecting a sufficient number of progressive motile and slightly increasing the number of follicles. The success rate of this IVF technique is estimated at 10-15%. The couple’s pre-IVF diagnosis will set the choice of this IVF technique.

IVF treatment : Fécondation In Vitro Classique FIV

Assisted reproductive techniques offer a glimmer of hope for couples facing fertility challenges, with Classical In Vitro Fertilization (IVF) shining as a particularly promising option. In contrast to intrauterine insemination (IUI). Classical IVF meticulously oversees the fertilization process in a controlled lab environment, greatly boosting the chances of success.

Classical In Vitro Fertilization process :how does Classical In Vitro Fertilization work?

The IVF cycle begins with ovarian stimulation followed by ovulation induction. The ultrasound-guided egg collection is performed 36 hours later. At the same time, the sperm is collected and prepared the day of the egg collection. The incubation of oocytes and sperm is done the same day at the IVF Center to give birth to several embryos.

The selection of embryos

During the complex process of selecting embryos, extensive scrutiny is carried out to pinpoint the most viable candidates. Once eggs are retrieved, a pivotal step occurs where the embryos are carefully curated and assessed. This critical selection stage is crucial, as it determines which embryos are best suited for transfer into the uterus.After harvesting the eggs, the embryo selection process usually takes place 2-5 days later and plays a crucial role in the path to conception. Choosing the most promising embryos from the batch, with a focus on the top two candidates (maximum two), is a critical decision. These carefully selected embryos offer the greatest potential for successful implantation and further growth.

Embryo transfer

The culmination of a complex process, embryo transfer marks the hopeful transition of carefully nurtured embryos from the laboratory to the prospective mother’s womb. It is a pivotal stage that holds great promise for the potential life that has been carefully cultivated to this point.As the last step in the IVF journey, the transfer of embryos represents the peak of a thoroughly planned process designed to enhance conception. It goes beyond a mere physical process, embodying the combination of scientific proficiency and the profound longing for parenthood.As the medical team prepares for the crucial moment of embryo transfer, a palpable sense of excitement and hope permeates the air. The carefully selected embryos, known as the « embryonic potential, » are gently implanted into the waiting womb. This is more than just a physical procedure; it is a meaningful transition, a unifying link between the sterile laboratory setting and the warm and nurturing sanctuary of the mother’s body.

IVF: Success rate of  this IVF technique

In the world of assisted reproductive technology, In Vitro Fertilization (IVF) offers a glimmer of hope for countless hopeful parents. With a success rate of 30-60%, this innovative method holds immense potential for building families.

IVF treatment: The couple’s pre-IVF diagnosis

When it comes to assisted reproductive technologies, a couple’s pre-IVF diagnosis is a crucial factor that heavily influences their journey to parenthood. This diagnostic phase acts as a guiding force, directing both medical experts and prospective parents towards the most suitable and successful In Vitro Fertilization (IVF) method.

ICSI: Intracytoplasmic Sperm Injection

ICSI cycle and classic IVF

The different stages of the ICSI cycle are the same as for a classic IVF cycle except for the fertilization technique in the laboratory. Indeed, for an ICSI, the carefully selected spermatozoon is directly injected into the oocyte whereas for a classic IVF, the spermatozoon penetrates the oocyte alone. This selection significantly increases the chances of success compared to conventional IVF.

ICSI cycle process :how does ICSI cycl work?

The ICSI cycle unfolds in a carefully planned and executed manner through several crucial stages. It all begins with stimulating the ovaries and inducing ovulation, setting the foundation for the intricate steps that come next.In the ICSI cycle, a critical turning point arrives 36 hours after the initial stage. This is when the highly precise procedure of ultrasound-guided egg retrieval occurs, paving the way for the remaining phases of the cycle. At the same time, all attention is focused on the pivotal task of sperm collection and preparation, which can occur either on the day of the egg retrieval or beforehand.

The next step in the ICSI cycle involves carefully incubating both oocytes and sperm simultaneously at the IVF Center in Tunis. Under close observation, specifically chosen sperm are precisely introduced into the oocyte using the ICSI technique. For situations that require extra attention, the IMSI technique is utilized, providing a thorough examination of sperm at a magnified level. As the ICSI cycle advances, the moment of truth arrives as embryos are meticulously chosen and inserted into the uterus 2 to 5 days after the egg retrieval. This pivotal step symbolizes the culmination of the entire process and brings with it the hope of a successful fertilization.

When it comes to IVF treatment, the ICSI technique’s success rate can vary between 30-70%. However, its effectiveness is ultimately dependent on the couple’s pre-IVF diagnosis, a crucial factor that influences their decision to choose this form of assisted reproductive technology. Throughout the intricate process of the ICSI cycle, every step plays a vital role in telling the story of hope, precision, and the relentless pursuit of a successful pregnancy.

Embryos Freezing

For IVF, ICSI and IMSI, if the couple develops a high number of embryos, they can choose to freeze the non-transferred embryos for several years. This allows the couple to try another IVF cycle without the need for egg or sperm collection. This will give the couple a second chance at a lower cost. Scientific studies show that there is no difference in the outcome of the MAP attempt or in the child conceived by a fresh or frozen embryo.

Testicular Sperm Extraction TESE

If the husband has difficulties with natural ejaculation, we can perform a testicular sperm extraction TESE. TESE is performed by urologists. It allows the extraction of sperm directly from the man’s testicles. It is performed on an outpatient basis. It can be performed on the same day as egg collection or before, in which case the extracted spermatozoa will be frozen.

What is the duration of stay for an ART or IVF cycle?

For the different IVF techniques and depending on the couple’s medical file, the average stay in Tunisia for an IVF cycle is 18-20 days. This duration can be much longer if the couple ventures alone and arrives in Tunisia without prior study of the medical file by a specialist. For most cases, the IVF protocol adapted to the couple starts with the beginning of the patient’s cycle. It is therefore important to prepare her medical file before departure. The date of arrival in Tunisia for an IVF cycle must be scheduled accordingly. In some cases, if the couple is followed by a gynecologist familiar with IVF techniques, the couple can start the treatment at his home country. The duration of stay for the IVF cycle in Tunisia is thus reduced to 10 days.

In Vitro Fertilization IVF cost :How much is In Vitro Fertilization IVF?

The price for an in vitro fertilization in Tunisia can vary from 1000 to 2800 eur depending on the technique chosen, the stimulation chosen, the examinations to be done and the specific treatments. Many couples choose to live in furnished studios next to the MAP centers. It is important to organize your medical stay before arrival because unfortunately, the logistical cost, airfare, accommodation, transportation, food is often higher than the cost of medical treatment. Tunisia Medical Travel can facilitate your stay in Tunisia and offer options adapted to your budget.

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